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>   首页   >   产品   >   一抗   >   精选抗体   >   磷酸化抗体   >   [KD]Phospho-CDC6 (Ser106) Rabbit mAb   

[KD]Phospho-CDC6 (Ser106) Rabbit mAb

     
  • 1 - [KD]Phospho-CDC6 (Ser106) Rabbit mAb AP75240
    Western blot analysis of Phospho-CDC6 (Ser106) in HeLa(WT) and Phospho-CDC6 (Ser106)-Knockdown HeLa(KD) using Phospho-CDC6 (Ser106) antibody.
  • 0 - [KD]Phospho-CDC6 (Ser106) Rabbit mAb AP75240
    Western blot analysis of Phospho-Cdc6 (Ser106) in Jurkat lysates using Phospho-CDC6 (Ser106) antibody.
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Product Information
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB
Primary Accession Q99741
Reactivity Human
Host Rabbit
Clonality Monoclonal Antibody
Isotype IgG
Conjugate Unconjugated
Purification Affinity Purified
Calculated MW 62720 Da
Additional Information
Gene ID 990
Other Names CDC6
Dilution WB~~1:500-1:1000
Format Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

For Research Use Only. Not For Use In Diagnostic Procedures.

Protein Information
Name CDC6
Synonyms CDC18L
Function Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Cellular Location Nucleus. Cytoplasm Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895).
Research Areas

BACKGROUND

Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication.

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